Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)
TISSUE(S): Spleen, Brain, Breast
DISEASE(S): Glioblastoma,Breast Cancer
SUBMITTER: Roberta Noberini
LAB HEAD: Tiziana Bonaldi
PROVIDER: PXD006027 | Pride | 2017-07-17
REPOSITORIES: Pride
Action | DRS | |||
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Glio1HEbrain.raw | Raw | |||
Glio1HExeno.raw | Raw | |||
Glio2HEbrain.raw | Raw | |||
Glio2HExeno.raw | Raw | |||
Glio3HEbrain.raw | Raw |
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Clinical epigenetics 20170711
<h4>Background</h4>Aberrations in histone post-translational modifications (hPTMs) have been linked with various pathologies, including cancer, and could not only represent useful biomarkers but also suggest possible targetable epigenetic mechanisms. We have recently developed an approach, termed pathology tissue analysis of histones by mass spectrometry (PAT-H-MS), that allows performing a comprehensive and quantitative analysis of histone PTMs from formalin-fixed paraffin-embedded pathology sa ...[more]