Proteomics

Dataset Information

0

Proteogenomic of Blastocystis sp. subtype 4 isolate WR1


ABSTRACT: description Blastocystis sp. is a highly prevalent anaerobic eukaryotic parasite of humans and animals. The genome of several representatives has been sequenced revealing specific traits such as an intriguing 3’-end processing of primary transcripts. We have acquired a first high-throughput proteomics dataset on the difficult to cultivate ST4 isolate WR1 and detected 2,761 proteins. We evidenced for the first time by proteogenomics a functional termination codon derived from transcript polyadenylation for seven different key cellular components.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Blastocystis

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean Armengaud

PROVIDER: PXD006588 | Pride | 2017-09-11

REPOSITORIES: pride

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Publications

Proteogenomic Insights into the Intestinal Parasite Blastocystis sp. Subtype 4 Isolate WR1.

Armengaud Jean J   Pible Olivier O   Gaillard Jean-Charles JC   Cian Amandine A   Gantois Nausicaa N   Tan Kevin S W KSW   Chabé Magali M   Viscogliosi Eric E  

Proteomics 20171016 21


Blastocystis sp. is known for years as a highly prevalent anaerobic eukaryotic parasite of humans and animals. Several monophyletic clades have been delineated based on molecular data, and the occurrence of each subtype in humans and/or animal hosts has been documented. The genome of several representatives has been sequenced revealing specific traits such as an intriguing 3'-end processing of primary transcripts. Here, a first high-throughput proteomics dataset acquired on this difficult-to-cul  ...[more]

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