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S.lividans TK24 sigma-factor deletions

ABSTRACT: Characterization of S.lividans TK24 secreted proteome changes upon deletion of certain sigma factors.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Streptomyces Lividans Tk24

SUBMITTER: Konstantinos Tsolis

LAB HEAD: Tassos Economou

PROVIDER: PXD006818 | Pride | 2019-02-16

REPOSITORIES: Pride

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			Action	DRS
	MQ_apl_files_sigma_factors.zip	Other
	MaxQuant_1.5.3.30.zip	Other
	SL000_set1_rep1.raw	Raw
	SL000_set1_rep2.raw	Raw
	SL000_set1_rep3.raw	Raw

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Publications

Secretome Dynamics in a Gram-Positive Bacterial Model.

Tsolis Konstantinos C KC Hamed Mohamed Belal MB Simoens Kenneth K Koepff Joachim J Busche Tobias T Rückert Christian C Oldiges Marco M Kalinowski Jörn J Anné Jozef J Kormanec Jan J Bernaerts Kristel K Karamanou Spyridoula S Economou Anastassios A

Molecular & cellular proteomics : MCP 20181129 3

Protein secretion is a central biological process in all organisms. Most studies dissecting bacterial secretion mechanisms have focused on Gram-negative cell envelopes such as that of <i>Escherichia coli</i> However, proteomics analyses in Gram negatives is hampered by their outer membrane. Here we studied protein secretion in the Gram-positive bacterium <i>Streptomyces lividans</i> TK24, in which most of the secretome is released in the growth medium. We monitored changes of the secretome as a ...[more]

PMID: 30498012

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