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Cross-linking MS data of CtNup82-Y complex

ABSTRACT: XL-MS Data of the in vitro reconstituted CtNup82-Y complex.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Chaetomium Thermophilum

SUBMITTER: Alexander von Appen

LAB HEAD: Martin Beck

PROVIDER: PXD007043 | Pride | 2018-10-17

REPOSITORIES: Pride

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			Action	DRS
	AvA_Y_214_05_1_1.mzXML	Mzxml
	AvA_Y_214_05_1_2.mzXML	Mzxml
	AvA_Y_214_05_2_1.mzXML	Mzxml
	AvA_Y_214_05_2_2.mzXML	Mzxml
	AvA_Y_214_05_3_1.mzXML	Mzxml

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Publications

A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex.

Teimer Roman R Kosinski Jan J von Appen Alexander A Beck Martin M Hurt Ed E

Nature communications 20171024 1

Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs), which are formed from multiple copies of ~30 different nucleoporins (Nups) and inserted into the double nuclear membrane. Many of these Nups are organized into subcomplexes, of which the Y-shaped Nup84 complex is the major constituent of the nuclear and cytoplasmic rings. The Nup82-Nup159-Nsp1 complex is another module that, however, is only assembled into the cytoplasmic ring. By means of crosslinking mass spectrometry, b ...[more]

PMID: 29062044

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