Proteomics

Dataset Information

0

Effects of thermal stress on Lactobacillus casei GCRL163


ABSTRACT: Identification of biomarkers and mechanisms of adaptation to prolonged thermal stress in L casei strain GCRL163

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Escherichia Coli

TISSUE(S): Cell Culture

SUBMITTER: Richard Wilson  

LAB HEAD: Dr Richard Wilson

PROVIDER: PXD007097 | Pride | 2018-11-04

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
G30_1.raw Raw
G30_1.zip Other
G30_2.raw Raw
G30_2.zip Other
G30_3.raw Raw
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Publications

Proteomic analysis of Lactobacillus casei GCRL163 cell-free extracts reveals a SecB homolog and other biomarkers of prolonged heat stress.

Adu Kayode T KT   Wilson Richard R   Nichols David S DS   Baker Anthony L AL   Bowman John P JP   Britz Margaret L ML  

PloS one 20181025 10


Prolonged heat stress is one of the harsh conditions Lactobacillus casei strains encounter as non-starter lactic acid bacteria in dairy product manufacture. To understand the physiological and molecular mechanisms through which Lb. casei GCRL163 adapts to persistent elevated temperature, label-free quantitative proteomics of cell-free extracts was used to characterize the global responses of the strain cultured anaerobically in bioreactors at 30 to 45°C, pH 6.5, together with GC-MS for fatty aci  ...[more]

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