Proteomics

Dataset Information

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Systematic Analysis of the Cerebrospinal Fluid Proteome of Fibromyalgia patients


ABSTRACT: Fibromyalgia (FM) is a syndrome characterized by widespread muscular pain, fatigue and functional symptoms, which is known to be difficult to diagnose as the various symptoms overlap with many other conditions. Currently, there are no biomarkers for FM, and the diagnosis is made subjectively by the clinicians. We have performed shotgun proteomics on cerebrospinal fluid (CSF) from FM patients and non-pain controls to find potential biomarker candidates for this syndrome.

INSTRUMENT(S): LTQ FT

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cerebrospinal Fluid

DISEASE(S): Fibromyalgia

SUBMITTER: Payam Emami Khoonsari  

LAB HEAD: Kim Kultima

PROVIDER: PXD008076 | Pride | 2018-04-25

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
Control_1.mzML Mzml
Control_1.mzid.gz Mzid
Control_10.mzML Mzml
Control_10.mzid.gz Mzid
Control_11.mzML Mzml
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Publications

Systematic analysis of the cerebrospinal fluid proteome of fibromyalgia patients.

Khoonsari Payam Emami PE   Musunri Sravani S   Herman Stephanie S   Svensson Camilla I CI   Tanum Lars L   Gordh Torsten T   Kultima Kim K  

Journal of proteomics 20180412


Fibromyalgia (FM) is a syndrome characterized by widespread muscular pain, fatigue and functional symptoms, which is known to be difficult to diagnose as the various symptoms overlap with many other conditions. Currently, there are no biomarkers for FM, and the diagnosis is made subjectively by the clinicians. We have performed shotgun proteomics on cerebrospinal fluid (CSF) from FM patients and non-pain controls to find potential biomarker candidates for this syndrome. Based on our multivariate  ...[more]

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