Proteomics

Dataset Information

0

Plasmodium falciparum schizont proteome


ABSTRACT: Proteome of the human malaria parasite Plasmodium falciparum at schizont life cycle stage during blood stage development

INSTRUMENT(S): LTQ FT

ORGANISM(S): Plasmodium Falciparum Palo Alto/uganda

TISSUE(S): Erythrocyte

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: Edwin Lasonder  

LAB HEAD: Edwin Lasonder

PROVIDER: PXD008250 | Pride | 2018-02-13

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
20090117EL02.RAW Raw
20090117EL03.RAW Raw
20090117EL04.RAW Raw
20090117EL05.RAW Raw
20090117EL06.RAW Raw
Items per page:
1 - 5 of 95
altmetric image

Publications

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity.

Stone Will J R WJR   Campo Joseph J JJ   Ouédraogo André Lin AL   Meerstein-Kessel Lisette L   Morlais Isabelle I   Da Dari D   Cohuet Anna A   Nsango Sandrine S   Sutherland Colin J CJ   van de Vegte-Bolmer Marga M   Siebelink-Stoter Rianne R   van Gemert Geert-Jan GJ   Graumans Wouter W   Lanke Kjerstin K   Shandling Adam D AD   Pablo Jozelyn V JV   Teng Andy A AA   Jones Sophie S   de Jong Roos M RM   Fabra-García Amanda A   Bradley John J   Roeffen Will W   Lasonder Edwin E   Gremo Giuliana G   Schwarzer Evelin E   Janse Chris J CJ   Singh Susheel K SK   Singh Susheel K SK   Theisen Michael M   Felgner Phil P   Marti Matthias M   Drakeley Chris C   Sauerwein Robert R   Bousema Teun T   Jore Matthijs M MM  

Nature communications 20180208 1


Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito, when they are ingested in an infectious blood meal. Here, we determine the transmission-reducing activity (TRA) of naturally acquired antibodies from 648 malaria-exposed individuals using lab-based mosquito-feeding assays. Transmission inhibition is significantly associated with antibody responses to Pfs48/45, Pfs230, and to 43 novel gametocyte proteins assessed by protein microarray. In field-based m  ...[more]

Similar Datasets

2022-07-05 | PXD033834 | Pride
2015-04-29 | PXD001623 | Pride
2017-03-13 | PXD005021 | Pride
2024-07-25 | PXD052657 | Pride
2011-04-25 | E-MTAB-636 | biostudies-arrayexpress
2024-06-21 | PXD048811 | Pride
2021-11-03 | PXD027302 | Pride
2011-03-16 | E-GEOD-25656 | biostudies-arrayexpress
2021-09-03 | E-MTAB-10773 | biostudies-arrayexpress
2021-09-03 | E-MTAB-10775 | biostudies-arrayexpress