Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, LTQ Orbitrap Velos, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Diploid Cell
SUBMITTER: Georg Kustatscher
LAB HEAD: Juri Rappsilber
PROVIDER: PXD008888 | Pride | 2019-11-11
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 830 |
Kustatscher Georg G Grabowski Piotr P Schrader Tina A TA Passmore Josiah B JB Schrader Michael M Rappsilber Juri J
Nature biotechnology 20191104 11
Assigning functions to the vast array of proteins present in eukaryotic cells remains challenging. To identify relationships between proteins, and thereby enable functional annotation of proteins, we determined changes in abundance of 10,323 human proteins in response to 294 biological perturbations using isotope-labeling mass spectrometry. We applied the machine learning algorithm treeClust to reveal functional associations between co-regulated human proteins from ProteomeHD, a compilation of o ...[more]