Dataset Information

Citrobacter rodentium ICC168 CPX SILAC

ABSTRACT: SILAC experiment to investigate proteome changes in response to the disruption of CPX in Citrobacter rodentium ICC168.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Citrobacter Rodentium Icc168

SUBMITTER: Nichollas Scott

LAB HEAD: Leonard J Foster

PROVIDER: PXD009049 | Pride | 2019-01-07

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	MQ_output.zip	Other
	Nsco_Citro_CPX_rep1_fraction01.raw	Raw
	Nsco_Citro_CPX_rep1_fraction02.raw	Raw
	Nsco_Citro_CPX_rep1_fraction03.raw	Raw
	Nsco_Citro_CPX_rep1_fraction04.raw	Raw

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Publications

Characterization of the Citrobacter rodentium Cpx regulon and its role in host infection.

Vogt Stefanie L SL Scholz Roland R Peng Yun Y Guest Randi L RL Scott Nichollas E NE Woodward Sarah E SE Foster Leonard J LJ Raivio Tracy L TL Finlay B Brett BB

Molecular microbiology 20190211 3

Envelope-localized proteins, such as adhesins and secretion systems, play critical roles in host infection by Gram-negative pathogens. As such, their folding is monitored by envelope stress response systems. Previous studies demonstrated that the Cpx envelope stress response is required for virulence of Citrobacter rodentium, a murine pathogen used to model infections by the human pathogens enteropathogenic and enterohemorrhagic Escherichia coli; however, the mechanisms by which the Cpx response ...[more]

PMID: 30536519

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