Dataset Information
Proteomic analysis of extracellular vesicles (EVs) from 4T1 breast cancer cells upon paclitaxel treatment
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL1109130000MODEL1311110000MODEL1909260003MODEL1311110001MODEL1909260004MODEL1703310000MODEL1909260005MODEL1909260006
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Permanent Cell Line Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: 
Chiara Cianciaruso
LAB HEAD: Michele De Palma
PROVIDER: PXD010362 | Pride | 2019-01-02
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| IK_160321_Elite_4TI_Cremo_01.dta | Other | |||
| IK_160321_Elite_4TI_Cremo_01.raw | Raw | |||
| IK_160321_Elite_4TI_Cremo_02.dta | Other | |||
| IK_160321_Elite_4TI_Cremo_02.raw | Raw | |||
| IK_160321_Elite_4TI_PTX_01.dta | Other |
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Publications
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models.
Nature cell biology 20181231 2
Cytotoxic chemotherapy is an effective treatment for invasive breast cancer. However, experimental studies in mice also suggest that chemotherapy has pro-metastatic effects. Primary tumours release extracellular vesicles (EVs), including exosomes, that can facilitate the seeding and growth of metastatic cancer cells in distant organs, but the effects of chemotherapy on tumour-derived EVs remain unclear. Here we show that two classes of cytotoxic drugs broadly employed in pre-operative (neoadjuva ...[more]
