Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mycobacterium Tuberculosis H37rv
TISSUE(S): Cell Culture
SUBMITTER: Jin Wang
LAB HEAD: Jin Wang
PROVIDER: PXD010984 | Pride | 2018-12-19
REPOSITORIES: Pride
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Pei Zenglin Z Wu Kang K Li Zehuan Z Li Chaoqun C Zeng Ling L Li Feng F Pei Ning N Liu Hongmei H Zhang Shu-Lin SL Song Yan-Zheng YZ Zhang Xiaoyan X Xu Jianqing J Fan Xiao-Yong XY Wang Jin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20181127
<h4>Background and purpose</h4>Tuberculosis is one of the most highly fatal diseases worldwide, and one-third of the world's population has been infected with Mycobacterium tuberculosis (M. tuberculosis). A previous study showed that M. tuberculosis was highly susceptible to being killed by ascorbate (i.e. vitamin C, VC), but the molecular mechanisms of the bactericidal activity of VC against M. tuberculosis are still not well understood.<h4>Experimental approach</h4>We assayed the effects of VC ...[more]