Ontology highlight
ABSTRACT:
INSTRUMENT(S): 6520 Quadrupole Time-of-Flight LC/MS
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Liver
SUBMITTER: Cole Michel
LAB HEAD: Kristofer Scott Fritz
PROVIDER: PXD012089 | Pride | 2019-01-23
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 128 |
Ali Hadi R HR Assiri Mohammed A MA Harris Peter S PS Michel Cole R CR Yun Youngho Y Marentette John O JO Huynh Frank K FK Orlicky David J DJ Shearn Colin T CT Saba Laura M LM Reisdorph Richard R Reisdorph Nichole N Hirschey Matthew D MD Fritz Kristofer S KS
Journal of proteome research 20190131 4
Mitochondrial dysfunction is one of many key factors in the etiology of alcoholic liver disease (ALD). Lysine acetylation is known to regulate numerous mitochondrial metabolic pathways, and recent reports demonstrate that alcohol-induced protein acylation negatively impacts these processes. To identify regulatory mechanisms attributed to alcohol-induced protein post-translational modifications, we employed a model of alcohol consumption within the context of wild type (WT), sirtuin 3 knockout (S ...[more]