Dataset Information

PREDICTIVE MODELING OF THERAPEUTIC RESPONSE TO CHONDROITIN SULFATE/GLUCOSAMINE HYDROCHLORIDE IN KNEE OSTEOARTHRITIS

ABSTRACT: In the present study we explored potential protein biomarkers useful to predict the therapeutic response of osteoarthritis (OA) patients treated with pharmaceutical grade Chondroitin sulfate/Glucosamine hydrochloride (CS+GH; Droglican, Bioiberica), in order to optimize therapeutic outcomes.

INSTRUMENT(S): 4800 Proteomics Analyzer

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

SUBMITTER: valentina calamia

LAB HEAD: Francisco J Blanco Garcia

PROVIDER: PXD012444 | Pride | 2019-09-12

REPOSITORIES: Pride

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Publications

Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis.

Blanco Francisco J FJ Camacho-Encina María M González-Rodríguez Lucía L Rego-Pérez Ignacio I Mateos Jesús J Fernández-Puente Patricia P Lourido Lucía L Rocha Beatriz B Picchi Florencia F Silva-Díaz María T MT Herrero Marta M Martínez Helena H Verges Josep J Ruiz-Romero Cristina C Calamia Valentina V

Therapeutic advances in chronic disease 20190824

<h4>Background</h4>In the present study, we explored potential protein biomarkers useful to predict the therapeutic response of knee osteoarthritis (KOA) patients treated with pharmaceutical grade Chondroitin sulfate/Glucosamine hydrochloride (CS+GH; Droglican, Bioiberica), in order to optimize therapeutic outcomes.<h4>Methods</h4>A shotgun proteomic analysis by iTRAQ labelling and liquid chromatography-mass spectrometry (LC-MS/MS) was performed using sera from 40 patients enrolled in the Multic ...[more]

PMID: 31489155

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	2FFrac21_24_3.mzML	Mzml
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	2Frac21_24_14.mzML	Mzml
	2Frac21_24_15.mzML	Mzml
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