Dataset Information
Arsenic induces reversible nitrosative stress and behavioural changes in mice
Ontology highlight
ABSTRACT:
INSTRUMENT(S): orbitrap
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: 
Haitham Amal
LAB HEAD: Steven Tannenbaum
PROVIDER: PXD012691 | Pride | 2021-09-08
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 1ppm.zip | Other | |||
| H1_1.raw | Raw | |||
| H1_2.raw | Raw | |||
| H2_1_mod.raw | Raw | |||
| L1_1.raw | Raw |
Items per page: 1 - 5 of 19 |
Publications
Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide.
International journal of molecular sciences 20200531 11
<h4>Background</h4>Accumulating public health and epidemiological literature support the hypothesis that arsenic in drinking water or food affects the brain adversely.<h4>Methods</h4>Experiments on the consequences of nitric oxide (NO) formation in neuronal cell culture and mouse brain were conducted to probe the mechanistic pathways of nitrosative damage following arsenic exposure.<h4>Results</h4>After exposure of mouse embryonic neuronal cells to low doses of sodium arsenite (SA), we found tha ...[more]
