Proteomics

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Profiling transcriptome and proteome of orange-spotted grouper (Epinephelus coioides) after nervous necrosis virus infection


ABSTRACT: Grouper is an important commercial maricultural fish, which suffer viral nervous necrosis (VNN) disease at the larval and juvenile stages, but the changes of transcriptomics and proteomics during viral infection remain unknown. In this study, we applied RNA-seq and label-free mass spectrum for the first time to depict the map of transcriptomics and proteomics in non-infected, susceptible-infected and tolerate-infected grouper in larval stage. Further analyses showed that the transcriptome and proteome change dramatically among 3 distinct groups, indicating that different immune response for infected and perststent grouper in larval stage. These valuable transcriptomics and proteomics datasets enable the investigation of molecular mechanism in nervous necrosis (VNN) virus infection, thus helps the further development of molecular breeding and marine fishery

INSTRUMENT(S): Q Exactive

ORGANISM(S): Epinephelus Coioides

TISSUE(S): Whole Body, Diploid Cell

SUBMITTER: hui Ge  

LAB HEAD: Ge Hui

PROVIDER: PXD012763 | Pride | 2019-05-15

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
P17627_B_C1_F1.raw Raw
P17627_B_C1_F2.raw Raw
P17627_B_C1_F3.raw Raw
P17627_B_C1_F4.raw Raw
P17627_B_C1_F5.raw Raw
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