Ontology highlight
ABSTRACT:
INSTRUMENT(S): solariX, 4800 Proteomics Analyzer
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Stem Cell, Bone Marrow
DISEASE(S): Osteoarthritis
SUBMITTER: Beatriz Rocha
LAB HEAD: Francisco Javier Blanco García
PROVIDER: PXD012879 | Pride | 2020-01-27
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
628OA_1_2_2.mzML | Mzml | |||
628OA_1_2_6.mzML | Mzml | |||
628OA_1_2_7.mzML | Mzml | |||
628OA_3_4_5_6_10.mzML | Mzml | |||
628OA_3_4_5_6_11.mzML | Mzml |
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Molecular & cellular proteomics : MCP 20200124 4
In osteoarthritis (OA), impairment of cartilage regeneration can be related to a defective chondrogenic differentiation of mesenchymal stromal cells (MSCs). Therefore, understanding the proteomic- and metabolomic-associated molecular events during the chondrogenesis of MSCs could provide alternative targets for therapeutic intervention. Here, a SILAC-based proteomic analysis identified 43 proteins related with metabolic pathways whose abundance was significantly altered during the chondrogenesis ...[more]