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CD4_TMT

ABSTRACT: A Study of the Global Proteomics by Differentiation of cd4+Tcell

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Helper T-lymphocyte

SUBMITTER: Min Jung Kim

LAB HEAD: Min-Sik Kim

PROVIDER: PXD013361 | Pride | 2022-05-19

REPOSITORIES: Pride

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			Action	DRS
	MSK_CD4_TMT_TP_Set1_bRPLC_F01.raw	Raw
	MSK_CD4_TMT_TP_Set1_bRPLC_F02.raw	Raw
	MSK_CD4_TMT_TP_Set1_bRPLC_F03.raw	Raw
	MSK_CD4_TMT_TP_Set1_bRPLC_F04.raw	Raw
	MSK_CD4_TMT_TP_Set1_bRPLC_F05.raw	Raw

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Publications

Multi-omics protein-coding units as massively parallel Bayesian networks: Empirical validation of causality structure.

Zenere Alberto A Rundquist Olof O Gustafsson Mika M Altafini Claudio C

iScience 20220311 4

In this article we use high-throughput epigenomics, transcriptomics, and proteomics data to construct fine-graded models of the "protein-coding units" gathering all transcript isoforms and chromatin accessibility peaks associated with more than 4000 genes in humans. Each protein-coding unit has the structure of a directed acyclic graph (DAG) and can be represented as a Bayesian network. The factorization of the joint probability distribution induced by the DAGs imposes a number of conditional in ...[more]

PMID: 35355520

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