Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Ovarian Cancer Cell
SUBMITTER: Jianying Guo
LAB HEAD: Haiteng Deng
PROVIDER: PXD013811 | Pride | 2019-09-09
REPOSITORIES: Pride
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Scientific reports 20190902 1
Ovarian cancer (OC) is the most lethal gynecological carcinoma due to the lack of diagnostic markers and effective drug targets. Discovery of new therapeutic targets in OC to improve the treatment outcome is urgently needed. We performed proteomic analysis of OC specimens and the paired normal tissues and revealed that proteins associated with mitochondrial proteostasis and protein translation were highly expressed in ovarian tumor tissues, indicating that mitochondria are required for tumor pro ...[more]