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SWATH-MS proteomic analysis of primary human keratinocytes exposed to Cannabidiol

ABSTRACT: Primary human keratinocytes cultures were incubated with either DMSO or cannabidiol (10 uM) for 24 hours (N=4) to evaluate the effect of this compound over skin cells.

OTHER RELATED OMICS DATASETS IN: GSE131565

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Keratinocyte

SUBMITTER: Martin Garrido-Rodríguez

LAB HEAD: Eduardo Munoz

PROVIDER: PXD013956 | Pride | 2019-10-16

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	CBD_1.wiff	Wiff
	CBD_1.wiff.scan	Wiff
	CBD_2.wiff	Wiff
	CBD_2.wiff.scan	Wiff
	CBD_3.wiff	Wiff

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Publications

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1.

Casares Laura L García Víctor V Garrido-Rodríguez Martín M Millán Estrella E Collado Juan A JA García-Martín Adela A Peñarando Jon J Calzado Marco A MA de la Vega Laureano L Muñoz Eduardo E

Redox biology 20190905

Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great attention for its therapeutic potential against different pathologies including skin diseases. However, although the efficacy in preclinical models and the clinical benefits of CBD in humans have been extensively demonstrated, the molecular mechanism(s) and targets responsible for these effects are as yet unknown. Herein we characterized at the molecular level the effects of CBD on primary human keratinocytes u ...[more]

PMID: 31518892

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