Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Serum
DISEASE(S): Dengue Disease,Zika Fever
SUBMITTER: Shuvadeep Maity
LAB HEAD: Christine Vogel
PROVIDER: PXD015422 | Pride | 2021-03-09
REPOSITORIES: Pride
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Molecular & cellular proteomics : MCP 20210212
Distinguishing between Zika and dengue virus infections is critical for accurate treatment, but we still lack detailed understanding of their impact on their host. To identify new protein signatures of the two infections, we used next-generation proteomics to profile 122 serum samples from 62 Zika and dengue patients. We quantified >500 proteins and identified 13 proteins that were significantly differentially expressed (adjusted p-value < 0.05). These proteins typically function in infection an ...[more]