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Olfactory proteomics in Dementia with Lewy bodies

ABSTRACT: Proteomic analysis were performed in olfactory bulbs derived from controls and individuals with dementia with lewy bodies

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Lewy Body Dementia

SUBMITTER: Enrique SantamarÃa

LAB HEAD: ENRIQUE SANTAMARIA

PROVIDER: PXD016069 | Pride | 2021-09-08

REPOSITORIES: Pride

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			Action	DRS
	20161219_LU40.raw	Raw
	20161219_LU41.raw	Raw
	20161219_LU42.raw	Raw
	20161219_LU43.raw	Raw
	20161219_LU44.raw	Raw

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1 - 5 of 15

Publications

Proteomic Characterization of the Olfactory Molecular Imbalance in Dementia with Lewy Bodies.

Lachén-Montes Mercedes M Mendizuri Naroa N Schvartz Domitille D Fernández-Irigoyen Joaquín J Sánchez Jean Charles JC Santamaría Enrique E

International journal of molecular sciences 20200902 17

Olfactory dysfunction is one of the prodromal symptoms in dementia with Lewy bodies (DLB). However, the molecular pathogenesis associated with decreased smell function remains largely undeciphered. We generated quantitative proteome maps to detect molecular alterations in olfactory bulbs (OB) derived from DLB subjects compared to neurologically intact controls. A total of 3214 olfactory proteins were quantified, and 99 proteins showed significant alterations in DLB cases. Protein interaction net ...[more]

PMID: 32887355

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Quantitative comparison of CSF proteins from T. b. gambiense and T. b. rhodesiense HAT patients

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A Tandem Mass Tag (TMT) proteomic analysis during the early phase of experimental pancreatitis

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2019-07-12 | PXD013466 | Pride

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