An interactive predictor to reassess the specific protein compositions of HIV-1 and extracellular vesicles
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ABSTRACT: HIV-infected T cells secrete simultaneously viral particles and small extracellular vesicles (sEVs) including MVB-derived exosomes and plasma membrane-derived EVs. sEVs and HIV share many physical and chemical characteristics, which makes their separation difficult.. Here, we used a global and un-biased proteomic approach to identify novel specific markers of the virus or sEV subtypes secreted by a human T lymphoma cell line.
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Helper T Cell
DISEASE(S): Human Immunodeficiency Virus Infectious Disease
SUBMITTER: Valentin SABATET
LAB HEAD: Damarys Loew
PROVIDER: PXD016626 | Pride | 2021-01-04
REPOSITORIES: Pride
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