Dataset Information

Exposure of cells to glyphosate and formulations including glyphosate

ABSTRACT: MUTZ-3-derived cells were exposed to different substances for 24h and sampled for proteome analysis.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Dendritic Cell

SUBMITTER: Fredrik Levander

LAB HEAD: Fredrik Levander

PROVIDER: PXD016859 | Pride | 2020-03-10

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	180705__Tim_Sample_13_15k_2um_New_15cmcolumn_80min_01.mgf	Mgf
	180705__Tim_Sample_13_15k_2um_New_15cmcolumn_80min_01.mgf.mzid.gz	Mzid
	180705__Tim_Sample_13_15k_2um_New_15cmcolumn_80min_01.mgf.pride.mztab.gz	Mztab
	180705__Tim_Sample_13_15k_2um_New_15cmcolumn_80min_01.pride.mgf.gz	Mgf
	180705__Tim_Sample_13_15k_2um_New_15cmcolumn_80min_01.raw	Raw

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Publications

An integrated transcriptomic- and proteomic-based approach to evaluate the human skin sensitization potential of glyphosate and its commercial agrochemical formulations.

Lindberg Tim T de Ávila Renato Ivan RI Zeller Kathrin S KS Levander Fredrik F Eriksson Dennis D Chawade Aakash A Lindstedt Malin M

Journal of proteomics 20200130

We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression of 200 transcripts upon cell exposure to xenobiotics, was used for skin sensitization prediction. POEA and the formulations were classified as skin sensitizers while glyphosate alo ...[more]

PMID: 32006680

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