Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)
TISSUE(S): Neutrophil, Blood
DISEASE(S): Permanent Neonatal Diabetes Mellitus
SUBMITTER: Roxane Degroote
LAB HEAD: Cornelia Annette Deeg
PROVIDER: PXD017274 | Pride | 2020-06-04
REPOSITORIES: Pride
Items per page: 1 - 5 of 8 |
Journal of proteomics 20200527
INS<sup>C94Y</sup> transgenic pigs develop a stable diabetic phenotype early after birth and therefore allow studying the influence of hyperglycemia on primary immune cells in an early stage of diabetes mellitus in vivo. Since immune response is altered in diabetes mellitus, with deviant neutrophil function discussed as one of the possible causes in humans and mouse models, we investigated these immune cells in INS<sup>C94Y</sup> transgenic pigs and wild type controls at protein level. A total o ...[more]