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Proteomic analysis of collagen membrane and matrix

ABSTRACT: High-resolution shotgun proteomic analysis on two porcine collagen-based biomaterials designed for guided bone regeneration and soft tissue augmentation was perfomed. A porcine-derived collagen membrane and a collagen matrix derived from peritoneum and/or skin were digested, separated by nano-reverse-phase high-performance liquid chromatography, and peptides subjected to mass spectrometric detection and analysis

INSTRUMENT(S): Q Exactive

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Peritoneum

DISEASE(S): Wounds And Injuries

SUBMITTER: Goran Mitulović

LAB HEAD: Goran Mitulović

PROVIDER: PXD019298 | Pride | 2021-09-09

REPOSITORIES: Pride

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			Action	DRS
	LFQ_200303.msf	Msf
	LFQ_200303.mzML	Mzml
	LFQ_200303.mzid.gz	Mzid
	LFQ_200303.pride.mgf.gz	Mgf
	LFQ_200303.pride.mztab.gz	Mztab

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Publications

Proteomic Analysis of Porcine-Derived Collagen Membrane and Matrix.

Lee Jung-Seok JS Mitulović Goran G Panahipour Layla L Gruber Reinhard R

Materials (Basel, Switzerland) 20201117 22

Collagen membranes and matrices being widely used in guided bone regeneration and soft tissue augmentation have characteristic properties based on their composition. The respective proteomic signatures have not been identified. Here, we performed a high-resolution shotgun proteomic analysis on two porcine collagen-based biomaterials designed for guided bone regeneration and soft tissue augmentation. Three lots each of a porcine-derived collagen membrane and a matrix derived from peritoneum and/o ...[more]

PMID: 33212864

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