Dataset Information
Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL1109130000MODEL1909260003MODEL1909260004MODEL1703310000MODEL1909260005MODEL1909260006MODEL1311110000MODEL1311110001
INSTRUMENT(S): Q Exactive
ORGANISM(S): Sarcophilus Harrisii
TISSUE(S): Cell Culture
SUBMITTER: 
Sri Ramarathinam
LAB HEAD: Anthony Wayne Purcell
PROVIDER: PXD020614 | Pride | 2021-02-08
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 20170929_sr_DFT1_mhc_rep1_A1.raw | Raw | |||
| 20170929_sr_DFT1_mhc_rep1_A10.raw | Raw | |||
| 20170929_sr_DFT1_mhc_rep1_A2.raw | Raw | |||
| 20170929_sr_DFT1_mhc_rep1_A3.raw | Raw | |||
| 20170929_sr_DFT1_mhc_rep1_A4.raw | Raw |
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Publications
The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif.
Immunology 20210204 2
Transmissible cancers are malignant cells that can spread between individuals of a population, akin to both a parasite and a mobile graft. The survival of the Tasmanian devil, the largest remaining marsupial carnivore, is threatened by the remarkable emergence of two independent lineages of transmissible cancer, devil facial tumour (DFT) 1 and devil facial tumour 2 (DFT2). To aid the development of a vaccine and to interrogate how histocompatibility barriers can be overcome, we analysed the pept ...[more]
