Dataset Information
PRM-based quantitative proteomic analysis of mouse tissues, testicular cells and cell lines
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Spleen, Heart, Testis, Brain, Lung, Liver, Kidney
SUBMITTER: 
Yao liping
LAB HEAD: Xuejiang Guo
PROVIDER: PXD020922 | Pride | 2022-09-30
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| PRM-9mousetissues.zip | Other | |||
| PRM-Linearityanalysis-1.zip | Other | |||
| PRM-Linearityanalysis-2.zip | Other | |||
| PRM-N2a_GC1-ribosome.zip | Other | |||
| PRM-RPL39Lknockout-spermatids-17proteins.zip | Other |
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Publications
A male germ-cell-specific ribosome controls male fertility.
Nature 20221214 7941
Ribosomes are highly sophisticated translation machines that have been demonstrated to be heterogeneous in the regulation of protein synthesis<sup>1,2</sup>. Male germ cell development involves complex translational regulation during sperm formation<sup>3</sup>. However, it remains unclear whether translation during sperm formation is performed by a specific ribosome. Here we report a ribosome with a specialized nascent polypeptide exit tunnel, Ribosome<sup>ST</sup>, that is assembled with the m ...[more]
