Proteomics

Dataset Information

0

Identification of HLA class I-presented peptides in MSI CRC model cell line HCT-116


ABSTRACT: HCT-116 cells were treated either with 5 µM of the NMD inhibitor 5-azacytidine (PMID: 25319547) or DMSO (negative solvent control) for 24 h to examine differences in HLA class I-mediated peptide presentation. Moreover, data were used for the identification of tumor-specific neoepitopes originating from insertion/deletion mutations due to microsatellite instability.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

DISEASE(S): Colon Cancer

SUBMITTER: Jonas Becker  

LAB HEAD: Andreas E. Kulozik

PROVIDER: PXD021755 | Pride | 2021-04-14

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
CCLE-mutations-HCT116.fasta Fasta
COSMIC-mutations-HCT116.fasta Fasta
Lara_190212_P0814_MR_JB_HA1_HCD_R1.raw Raw
Lara_190212_P0814_MR_JB_HA2_HCD_R1.raw Raw
Lara_190212_P0814_MR_JB_HA3_HCD_R1.raw Raw
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