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Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis

ABSTRACT: Here we investigate the possible relationship between the propagation of epigenetic information and the developmental cell proliferation during Xenopus embryogenesis. We systemically inhibited cell proliferation during the G1/S-transition in gastrula embryos and followed their development until the tadpole stage. We quantified by mass spectrometry the abundance of a large set of histone modification states, which reflects the developmental maturation of the embryonic epigenome.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Xenopus Laevis (african Clawed Frog)

TISSUE(S): Embryo

SUBMITTER: Daniil Pokrovsky

LAB HEAD: Ralph AW Rupp

PROVIDER: PXD021803 | Pride | 2021-08-06

REPOSITORIES: Pride

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			Action	DRS
	20161013QexHF-inclusionlist_R10_Light.csv	Csv
	20170802Ref1225QexHF-inclusionlist_R10_Light.csv	Csv
	H3.sky	Other
	H3.sky.view	Other
	H3.skyd	Other

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