Chicken liver TMT-based proteomics
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Gallus Gallus (chicken)
TISSUE(S): Liver
SUBMITTER: 
Jianfei Chen
LAB HEAD: Xuemei Deng
PROVIDER: PXD022768 | Pride | 2021-09-09
REPOSITORIES: pride
Dataset's files
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| 13544B-1.raw | Raw | |||
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Items per page: 5 1 - 5 of 22 |
Publications
An EAV-HP insertion in the promoter region of SLCO1B3 has pleiotropic effects on chicken liver metabolism based on the transcriptome and proteome analysis.
Chen Jianfei J Hua Guoying G Han Deping D Zheng Xiaotong X Dong Xianggui X Wang Shuxiang S Long Junjiang J Zheng Zhonghua Z Wang Ailing A Wang Jiankui J Wang Xiaotong X Deng Xuemei X
Scientific reports 20210407 1
Solute carrier organic anion transporter 1B3 (SLCO1B3) is an important liver primarily highly expressed gene, its encoded protein (OATP1B3) involved in the transport of multi-specific endogenous and exogenous substances. We previously reported that an EAV-HP inserted mutation (IM+) in the 5' flanking region of SLCO1B3 was the causative mutation of chicken blue eggs, and a further research showed that IM+ significantly reduced the expression of SLCO1B3 in liver. Herein, we confirmed a cholate res ...[more]
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