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Identification of the protein interaction network of Stag proteins

ABSTRACT: This study involves the identification of specific Stag1 interactors with and without Cohesin loss. Stag1 was immunoprecipiated from human HCT116 cells, under 4 treatments - untreated (UTR), Non-specific siRNA treatment (SiCON), SA1 siRNA treatment (SiSA1) and Auxin treatment for Cohesin loss (IAA). An unspecific IgG pulldown was also conducted to assess for unspecific protein binding to the bead system (Mock). Significant proteins were determined by label-free quantification and statistical analysis using MaxQuant and MSstats.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Colon Cancer

SUBMITTER: Silvia Surinova

LAB HEAD: Silvia Surinova

PROVIDER: PXD024354 | Pride | 2023-04-18

REPOSITORIES: Pride

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			Action	DRS
	andromeda.zip	Other
	regmab2_QEP2_201005_049.raw	Raw
	regmab2_QEP2_201005_053.raw	Raw
	regmab2_QEP2_201005_057.raw	Raw
	regmab2_QEP2_201005_061.raw	Raw

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