Dataset Information

A comprehensive proteome and acetyl-proteome atlas from pre-laying to peak-laying stage in liver of hens (Gallus gallus)

ABSTRACT: TMT labeled proteome and acetylated proteome were used to reveal molecular mechanisms adapting to the physiological changes between pre- and peak-laying hens

INSTRUMENT(S): Q Exactive

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Liver

SUBMITTER: Zhang Wang

LAB HEAD: XiaoJun Liu

PROVIDER: PXD024718 | Pride | 2022-02-17

REPOSITORIES: Pride

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A Comprehensive Proteome and Acetyl-Proteome Atlas Reveals Molecular Mechanisms Adapting to the Physiological Changes From Pre-laying to Peak-Laying Stage in Liver of Hens (<i>Gallus gallus</i>).

Wang Zhang Z Wang Dandan D Jiang Keren K Guo Yulong Y Li Zhuanjian Z Jiang Ruirui R Han Ruili R Li Guoxi G Tian Yadong Y Li Hong H Kang Xiangtao X Liu Xiaojun X

Frontiers in veterinary science 20211021

Along with sexual maturity, the liver undergoes numerous metabolic processes to adapt the physiological changes associated with egg-laying in hens. However, mechanisms regulating the processes were unclear. In this study, comparative hepatic proteome and acetyl-proteome between pre- and peak-laying hens were performed. The results showed that the upregulated proteins were mainly related to lipid and protein biosynthesis, while the downregulated proteins were mainly involved in pyruvate metabolis ...[more]

PMID: 34746273

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	Z8525TPAc_MaxQuant.zip	Other