Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Trypanosoma Brucei
SUBMITTER: Dupuy Jean-William
LAB HEAD: Michael Boshart
PROVIDER: PXD025357 | Pride | 2022-08-17
REPOSITORIES: Pride
Action | DRS | |||
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Link_between_files.xlsx | Xlsx | |||
TriTrypDB-51_TbruceiTREU927_AnnotatedProteins.fasta | Fasta | |||
andromeda.zip | Other | |||
checksum.txt | Txt | |||
mb161027_01.raw | Raw |
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Bachmaier Sabine S Giacomelli Giacomo G Calvo-Alvarez Estefanía E Vieira Larissa Rezende LR Van Den Abbeele Jan J Aristodemou Aris A Lorentzen Esben E Gould Matt K MK Brennand Ana A Dupuy Jean-William JW Forné Ignasi I Imhof Axel A Bramkamp Marc M Salmon Didier D Rotureau Brice B Boshart Michael M
Nature communications 20220916 1
Signaling from ciliary microdomains controls developmental processes in metazoans. Trypanosome transmission requires development and migration in the tsetse vector alimentary tract. Flagellar cAMP signaling has been linked to parasite social motility (SoMo) in vitro, yet uncovering control of directed migration in fly organs is challenging. Here we show that the composition of an adenylate cyclase (AC) complex in the flagellar tip microdomain is essential for tsetse salivary gland (SG) colonizat ...[more]