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AKIRIN2 controls the nuclear import of proteasomes in vertebrates

ABSTRACT: AKIRIN2 is an essential negative regulator of nuclear protein, including oncogenic transcription factors such as MYC. To identify the mode of AKIRIN2-dependent nuclear protein regulation we performed pulldown and mass spectrometry of V5-tagged AKIRIN2 variants or nuclear GFP control.

INSTRUMENT(S): Orbitrap Fusion Lumos, Orbitrap Exploris 480, Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon

DISEASE(S): Colon Cancer

SUBMITTER: Richard Imre

LAB HEAD: Johannes Zuber

PROVIDER: PXD027184 | Pride | 2021-11-02

REPOSITORIES: pride

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			Action	DRS
	20191121_Lumos_RSLC5_DeAlmeida_Zuber_IMP_30per_control3xV5-GFP_01.raw	Raw
	20191121_Lumos_RSLC5_DeAlmeida_Zuber_IMP_30per_control3xV5-GFP_02.raw	Raw
	20191121_Lumos_RSLC5_DeAlmeida_Zuber_IMP_30per_control3xV5-GFP_03.raw	Raw
	20191121_Lumos_RSLC5_DeAlmeida_Zuber_IMP_30per_sample3xV5-AKI2_01.raw	Raw
	20191121_Lumos_RSLC5_DeAlmeida_Zuber_IMP_30per_sample3xV5-AKI2_02.raw	Raw

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