Dataset Information
Proteomic and phosphoproteomic profiling of aging human mammary myoepithelial and luminal epithelial cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Breast Epithelium, Breast
SUBMITTER: 
Stefan Hinz
LAB HEAD: Mark Labarge
PROVIDER: PXD027540 | Pride | 2021-11-03
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Antigoni_21dec19_LEP_Fenta.raw | Raw | |||
| Antigoni_21dec19_LEP_N1.raw | Raw | |||
| Antigoni_21dec19_LEP_N10.raw | Raw | |||
| Antigoni_21dec19_LEP_N11.raw | Raw | |||
| Antigoni_21dec19_LEP_N12.raw | Raw |
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Publications
Deep proteome profiling of human mammary epithelia at lineage and age resolution.
iScience 20210823 9
Age is the major risk factor in most carcinomas, yet little is known about how proteomes change with age in any human epithelium. We present comprehensive proteomes comprised of >9,000 total proteins and >15,000 phosphopeptides from normal primary human mammary epithelia at lineage resolution from ten women ranging in age from 19 to 68 years. Data were quality controlled and results were biologically validated with cell-based assays. Age-dependent protein signatures were identified using differe ...[more]
