Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Rajaraman Gopalakrishnan
LAB HEAD: Fred Winston
PROVIDER: PXD027708 | Pride | 2021-12-05
REPOSITORIES: Pride
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3188_z04397_tc-o238g-setB_MS3_static-TMT.mzid.gz | Mzid | |||
checksum.txt | Txt | |||
z04397_tc-o238g-setB_MS3.mgf | Mgf | |||
z04397_tc-o238g-setB_MS3.raw | Raw | |||
z04397_tc-o238g-setB_MS3_static-TMT.mzXML | Mzxml |
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Gopalakrishnan Rajaraman R Winston Fred F
The Journal of biological chemistry 20210917 4
The histone chaperone Spt6 is involved in promoting elongation of RNA polymerase II (RNAPII), maintaining chromatin structure, regulating cotranscriptional histone modifications, and controlling mRNA processing. These diverse functions of Spt6 are partly mediated through its interactions with RNAPII and other factors in the transcription elongation complex. In this study, we used mass spectrometry to characterize the differences in RNAPII-interacting factors between wildtype cells and those depl ...[more]