Proteomics

Dataset Information

0

Acetylation profiles in the metabolic process of glioma-associated seizures


ABSTRACT: We used label-free based mass spectrometry-based quantitative proteomics to quantify dynamic changes of protein acetylation between gliomas with seizure (CA1 group) and gliomas without seizure (CA2 group).We further classified acetylated proteins into groups according to cell component, molecular function and biological process. In addition, metabolic pathways and protein interaction networks were analyzed.

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Brain Glioma

SUBMITTER: Peisen yao  

LAB HEAD: Dezhi Kang

PROVIDER: PXD027864 | Pride | 2022-02-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Ac_CA1_1_Slot1-34_1_8388.d.zip Other
Ac_CA1_2_Slot1-35_1_8390.d.zip Other
Ac_CA1_3_Slot1-36_1_8392.d.zip Other
Ac_CA2_1_Slot1-37_1_8394.d.zip Other
Ac_CA2_2_Slot1-38_1_8396.d.zip Other
Items per page:
1 - 5 of 7
altmetric image

Publications

Acetylation Profiles in the Metabolic Process of Glioma-Associated Seizures.

Xu Ya-Wen YW   Lin Peng P   Zheng Shu-Fa SF   Huang Wen W   Lin Zhang-Ya ZY   Shang-Guan Huang-Cheng HC   Lin Yuan-Xiang YX   Yao Pei-Sen PS   Kang De-Zhi DZ  

Frontiers in neurology 20211001


<b>Objective:</b> We test the hypothesis that lysine acetylation is involved in the metabolic process of glioma-associated seizures (GAS). <b>Methods:</b> We used label-free mass spectrometry-based quantitative proteomics to quantify dynamic changes of protein acetylation between gliomas with seizure (CA1 group) and gliomas without seizure (CA2 group). Furthermore, differences of acetyltransferase and deacetylase expression between CA1 and CA2 groups were performed by a quantitative proteomic st  ...[more]

Similar Datasets

2005-12-29 | E-GEOD-3928 | biostudies-arrayexpress
2013-02-14 | E-GEOD-44031 | biostudies-arrayexpress
2011-02-13 | E-GEOD-27015 | biostudies-arrayexpress
2011-02-13 | E-GEOD-27166 | biostudies-arrayexpress
2015-12-31 | E-GEOD-74043 | biostudies-arrayexpress
2011-02-15 | E-GEOD-26511 | biostudies-arrayexpress
2020-04-16 | E-MTAB-8954 | biostudies-arrayexpress
2013-10-01 | E-GEOD-51260 | biostudies-arrayexpress
2019-07-23 | PXD014606 | Pride
2018-09-04 | E-MTAB-6134 | biostudies-arrayexpress