Proteomics

Dataset Information

0

In vivo BioID Mouse heart masspec data


ABSTRACT: Cardiac excitation-contraction (E-C) coupling requires dyads, the nanoscopic microdomains formed adjacent to Z-lines by apposition of transverse (T)-tubules and junctional sarcoplasmic reticulum (jSR). Disruption of dyad architecture and function are common features of diseased cardiomyocytes. However, little is known about the mechanisms that modulate dyad organization during cardiac homeostasis and disease. Here, we used proximity proteomics in intact, living hearts to identify proteins enriched near dyads.

INSTRUMENT(S): LTQ Orbitrap Velos, LTQ

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Heart

SUBMITTER: Fujian Lu  

LAB HEAD: William T. Pu

PROVIDER: PXD028960 | Pride | 2022-02-21

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
48534_73731.mzid.gz Mzid
48538_73733.mzid.gz Mzid
48539_73732.mzid.gz Mzid
73731-copy.mzXML Mzxml
73731.mzXML Mzxml
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