Dataset Information

Proteomic profiling of canine fibrosarcomas and adjacent unaffected peritumoral tissue using laser-capture microdissected FFPE tissue

ABSTRACT: Proteomic profiling of canine fibrosarcomas and adjacent unaffected peritumoral tissue using laser-capture microdissected FFPE tissue

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Skeletal Muscle, Ccd-18co Cell, Adipose Tissue, Connective Tissue

DISEASE(S): Fibrosarcoma

SUBMITTER: Laura Kunz

LAB HEAD: Enni Markkanen

PROVIDER: PXD029338 | Pride | 2023-03-11

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	20210308_002_S286176_MN1-F.raw	Raw
	20210308_003_S286175_MN1-M.raw	Raw
	20210308_004_S286174_MN1-T.raw	Raw
	20210308_005_S286177_MN1-CT.raw	Raw
	20210308_007_S286178_MN2-T.raw	Raw

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Publications

Proteomic profiling of canine fibrosarcoma and adjacent peritumoral tissue.

Beebe Erin E Pöschel Amiskwia A Kunz Laura L Wolski Witold W Motamed Zahra Z Meier Daniela D Guscetti Franco F Nolff Mirja C MC Markkanen Enni E

Neoplasia (New York, N.Y.) 20221209

Fibrosarcoma (FSA) are rare soft tissue tumors that display aggressive local behavior and invasive growth leading to high rates of tumor recurrence. While the low incidence in humans hampers detailed understanding of the disease, FSA are frequent in dogs and present potential models for the human condition. However, a lack of in-depth molecular characterization of FSA and unaffected peritumoral tissue (PTT) in both species impedes the translational potential of dogs. To address this shortcoming, ...[more]

PMID: 36508875

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