Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Xenopus Laevis (african Clawed Frog)
TISSUE(S): Egg
SUBMITTER: Aga Gambus
LAB HEAD: Aga Gambus
PROVIDER: PXD029705 | Pride | 2022-10-14
REPOSITORIES: Pride
Items per page: 1 - 5 of 60 |
The Journal of biological chemistry 20220704 8
Complex cellular processes are driven by the regulated assembly and disassembly of large multiprotein complexes. While we are beginning to understand the molecular mechanism for assembly of the eukaryotic DNA replication machinery (replisome), we still know relatively little about the regulation of its disassembly at replication termination. Recently, the first elements of this process have emerged, revealing that the replicative helicase, at the heart of the replisome, is polyubiquitylated prio ...[more]