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Metaproteomic profiling of the intestinal microbiota of the participants of the AGBRESA study

ABSTRACT: Application of a mass spectrometry -based approach to assess the gut microbiota composition and the associated metaproteomic functionality of subjects exposed to simulated microgravityduring the Artificial Gravity Bed Rest study (AGBRESA)

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Archaea Bacteria Viruses Eukaryota (eucaryotes)

SUBMITTER: Jean ARMENGAUD

LAB HEAD: Jean Armengaud

PROVIDER: PXD032387 | Pride | 2023-10-24

REPOSITORIES: Pride

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			Action	DRS
	F422717.dat	Other
	F422717_p0.05.mzid.gz	Mzid
	F422719.dat	Other
	F422719_p0.05.mzid.gz	Mzid
	F422721.dat	Other

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Publications

Human gut microbiome and metabolite dynamics under simulated microgravity.

Ramos-Nascimento Ana A Grenga Lucia L Haange Sven-Bastiaan SB Himmelmann Alexandra A Arndt Franca Sabine FS Ly Yen-Tran YT Miotello Guylaine G Pible Olivier O Jehmlich Nico N Engelmann Beatrice B von Bergen Martin M Mulder Edwin E Frings-Meuthen Petra P Hellweg Christine Elisabeth CE Jordan Jens J Rolle-Kampczyk Ulrike U Armengaud Jean J Moeller Ralf R

Gut microbes 20230925 2

The Artificial Gravity Bed Rest - European Space Agency (AGBRESA) study was the first joint bed rest study by ESA, DLR, and NASA that examined the effect of simulated weightlessness on the human body and assessed the potential benefits of artificial gravity as a countermeasure in an analog of long-duration spaceflight. In this study, we investigated the impact of simulated microgravity on the gut microbiome of 12 participants during a 60-day head-down tilt bed rest at the :envihab facilities. Ov ...[more]

PMID: 37749878

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