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Serum proteomic analysis by tandem mass tags-based quantitative proteomics in pediatric obstructive sleep apnea

ABSTRACT: Pediatric obstructive sleep apnea (OSA) is a frequent respiratory disorder with an estimated prevalence of 3–6% in the general population. However, the underlying pathophysiology of OSA remains unclear. Recently, proteomic analysis using high-resolution and high-throughput mass spectrometry has been widely used in the field of medical sciences. In the present study, tandem mass tags (TMT)-based proteomic analysis was performed in the serum of patients with OSA.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

SUBMITTER: Dongcai Li

LAB HEAD: Dongcai Li

PROVIDER: PXD032734 | Pride | 2022-05-20

REPOSITORIES: Pride

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Publications

Serum Proteomic Analysis by Tandem Mass Tag-Based Quantitative Proteomics in Pediatric Obstructive Sleep Apnea.

Cheng Hanrong H Jin Shoumei S Huang Simin S Hu Tianyong T Zhao Miao M Li Dongcai D Wu Benqing B

Frontiers in molecular biosciences 20220411

Pediatric obstructive sleep apnea (OSA) is a frequent respiratory disorder with an estimated prevalence of 3-6% in the general population. However, the underlying pathophysiology of OSA remains unclear. Recently, proteomic analysis using high-resolution and high-throughput mass spectrometry has been widely used in the field of medical sciences. In the present study, tandem mass tag (TMT)-based proteomic analysis was performed in the serum of patients with OSA. The proteomic analysis revealed a s ...[more]

PMID: 35480887

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