Dataset Information

Cornu aspersum Comparative Mucomics LC-MSMS

ABSTRACT: Here we apply an omics-style workflow to characterize the adhesive, lubricating, and protective mucus from Cornu aspersum snails. Through a combined transcriptomic, proteomic, and glycomic approach alongside the characterization of physical and chemical properties, we explain the origins of the functional differences between each of these biological materials.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Cornu Aspersum

TISSUE(S): Epithelial Cell, Pedal Muscle, Skin Epithelium

DISEASE(S): Disease Free

SUBMITTER: Antonio Cerullo

LAB HEAD: Adam Brian Braunschweig

PROVIDER: PXD035534 | Pride | 2023-10-24

REPOSITORIES: Pride

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Publications

Comparative mucomic analysis of three functionally distinct Cornu aspersum Secretions.

Cerullo Antonio R AR McDermott Maxwell B MB Pepi Lauren E LE Liu Zhi-Lun ZL Barry Diariou D Zhang Sheng S Yang Xu X Chen Xi X Azadi Parastoo P Holford Mande M Braunschweig Adam B AB

Nature communications 20230902 1

Every animal secretes mucus, placing them among the most diverse biological materials. Mucus hydrogels are complex mixtures of water, ions, carbohydrates, and proteins. Uncertainty surrounding their composition and how interactions between components contribute to mucus function complicates efforts to exploit their properties. There is substantial interest in commercializing mucus from the garden snail, Cornu aspersum, for skincare, drug delivery, tissue engineering, and composite materials. C. ...[more]

PMID: 37660066

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			Action	DRS
	Adhesive.mgf	Mgf
	Adhesive.raw	Raw
	Adhesive__F009225_.mzid.gz	Mzid
	Adhesive__F009225_.mzid_Adhesive__F009225_.MGF	Mzid
	Lubricating.mgf	Mgf