Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Primary Cell, Oligodendrocyte
SUBMITTER: Mable Lam
LAB HEAD: J. Bradley Zuchero
PROVIDER: PXD036174 | Pride | 2022-10-14
REPOSITORIES: Pride
Items per page: 1 - 5 of 51 |
Nature communications 20220923 1
Myelin is required for rapid nerve signaling and is emerging as a key driver of CNS plasticity and disease. How myelin is built and remodeled remains a fundamental question of neurobiology. Central to myelination is the ability of oligodendrocytes to add vast amounts of new cell membrane, expanding their surface areas by many thousand-fold. However, how oligodendrocytes add new membrane to build or remodel myelin is not fully understood. Here, we show that CNS myelin membrane addition requires e ...[more]