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Host biomarker discovery for ectoparasite resistance in cattle

ABSTRACT: This project aimed to discover the protein-based biomarkers for tick resistance in cattle using cattle serum samples. The cattle were phenotyped into two groups, tick-resistant and susceptible after an artificial tick challenge. Mean tick scores were used to categorise cattle. The SWATH analysis was sued to measure the relative abundance of proteins in skin samples of the two groups at different time points.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Skin

SUBMITTER: Ali Raza

LAB HEAD: Ala Tabor

PROVIDER: PXD036563 | Pride | 2023-01-25

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20201216_Ali_01_DDA_Brangus_Serum.swath	Other
	20201216_Ali_01_DDA_F1.wiff	Wiff
	20201216_Ali_01_DDA_F1.wiff.scan	Wiff
	20201216_Ali_01_DDA_Pooled_2.group	Other
	20201216_Ali_02_DDA_F2.wiff	Wiff

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Biomarker discovery for ectoparasite host resistance in cattle

Project description:This project aimed to discover the protein-based biomarkers for tick resistance in cattle using cattle skin samples. The cattle were phenotyped into two groups, tick-resistant and susceptible after artificial tick challenge. Mean tick scores were used to categorise cattle. The SWATH analysis was sued to measure the relative abundance of proteins in skin samples of the two groups at different time points.

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