Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Suspension Culture
SUBMITTER: Li Wang
LAB HEAD: Yanhui Xu
PROVIDER: PXD036708 | Pride | 2023-03-11
REPOSITORIES: Pride
Action | DRS | |||
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PBAF-NCP-1.raw | Raw | |||
PBAF-NCP-12.xlsx | Xlsx | |||
PBAF-NCP-2.raw | Raw | |||
PBAF-NCP-3.raw | Raw | |||
PBAF-NCP-3.xlsx | Xlsx |
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Wang Li L Yu Jiali J Yu Zishuo Z Wang Qianmin Q Li Wanjun W Ren Yulei Y Chen Zhenguo Z He Shuang S Xu Yanhui Y
Nature communications 20221210 1
BAF and PBAF are mammalian SWI/SNF family chromatin remodeling complexes that possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free regions for transcription activation. Despite previous structural studies and recent advance of SWI/SNF family complexes, it remains incompletely understood how PBAF-nucleosome complex is organized. Here we determined structure of 13-subunit human PBAF in complex with acetylated nucleosome in ADP-BeF<sub>3</sub>-bound state. Four PBAF-spe ...[more]