Quantitative proteome analysis to map the targets of small molecule UM171
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ABSTRACT: Earlier we identified the protein degradation properties of small molecule UM171 (Subramaniam et al., 2020, Blood). Here we employed quantitative proteomics approach to map the global targets of UM171. Our study revealed multiple targets including the members of CoREST complex such as RCOR1 and LSD1.
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Sudip Ghosh
LAB HEAD: Jenny Hansson
PROVIDER: PXD037999 | Pride | 2023-03-30
REPOSITORIES: Pride
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