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Intact Transition Epitope Mapping - Force differences between Original and Unusual Residues (ITEM-FOUR)

ABSTRACT: Human cardiac Troponin I epitope peptides were incubated with monoclonal anti-cardiac Troponin I antibody. Immune complexes were subjected to nano electrospray mass spectrometry in order to determine apparent binding energies and dissociation constants of immune complex dissociation reactions in the gas phase.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Heart

SUBMITTER: Michael Kreutzer

LAB HEAD: Prof. Dr. Michael O. Glocker

PROVIDER: PXD038365 | Pride | 2023-01-17

REPOSITORIES: Pride

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			Action	DRS
	10042018_PEPTID_1.dta	Other
	11042018_PEPTID_2_new.dta	Other
	11042018_PEPTID_3.dta	Other
	11042018_PEPTID_4.dta	Other
	11042018_PEPTID_5_new2.dta	Other

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Mass Spectrometric Analysis of Antibody-Epitope Peptide Complex Dissociation: Theoretical Concept and Practical Procedure of Binding Strength Characterization

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