Dataset Information

MRM Analysis of Cap, Ven and plasma

ABSTRACT: Samples were quantitatively analyzed by a liquid chromatography-multiple reaction monitoring-mass spectrometry method targeting 114 peptides representing 60 HSP proteins and by a data-independent acquisition mass spectrometry discovery method, resulting in up to 3,811 protein identifications. The data from the three biofluids indicate that remote collection devices are a viable option for personal blood proteome biosignature stratification and health analysis.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood

SUBMITTER: Stephen Whelan

LAB HEAD: Stephen Whelan

PROVIDER: PXD038678 | Pride | 2023-10-17

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	20220330_MitraHSP_C1WB-1.raw	Raw
	20220330_MitraHSP_C1WB-1_profile_out.tsv	Tabular
	20220330_MitraHSP_C1WB-2.raw	Raw
	20220330_MitraHSP_C1WB-2_profile_out.tsv	Tabular
	20220330_MitraHSP_C1WB-3.raw	Raw

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Publications

Assessment of a 60-Biomarker Health Surveillance Panel (HSP) on Whole Blood from Remote Sampling Devices by Targeted LC/MRM-MS and Discovery DIA-MS Analysis.

Whelan Stephen A SA Hendricks Nathan N Dwight Zachary L ZL Fu Qin Q Moradian Annie A Van Eyk Jennifer E JE Mockus Susan M SM

Analytical chemistry 20230630 29

Telehealth, accessing healthcare and wellness remotely, should be a cost-effective and efficient way for individuals to receive care. The convenience of having a reliable remote collection device for blood tests will facilitate access to precision medicine and healthcare. Herein, we tested a 60-biomarker health surveillance panel (HSP), containing 35 FDA/LDT assays and covering at least 14 pathological states, on 8 healthy individuals' ability to collect their own capillary blood from a lancet f ...[more]

PMID: 37389440

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