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Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function

ABSTRACT: Dysregulated mitochondrial function is a common feature in several malignancies, includingpancreatic cancer. Although mitochondria have their own genome, most mitochondrial proteins are nuclear-encoded and imported by a multi-subunit translocase of the outer mitochondrial membrane (TOMM). TOMM22 is the central receptor of the TOMM complex and plays a role incomplex assembly. We aim to understand the pathobiological roles of TOMM subunits in PC.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Pancreas

DISEASE(S): Pancreatic Cancer

SUBMITTER: SANTANU DASGUPTA

LAB HEAD: Santanu Dasgupta

PROVIDER: PXD040198 | Pride | 2023-10-25

REPOSITORIES: Pride

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			Action	DRS
	01_control.msfView	Msf
	01_control.raw	Raw
	01_knockdown.msfView	Msf
	01_knockdown.raw	Raw
	02_control.msfView	Msf

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